en ● Psychosocial Health مقاله اصيل پژوهشي Orginal Article <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Tahoma;"><span style="line-height:2;"><b>Background:</b> Polycystic Ovary Syndrome (PCOS) is a highly prevalent, chronic endocrine disorder affecting reproductive-age women, with estimates it impacts between 5% and 10% of this population globally. Married women with PCOS often face challenges, such as infertility and sexual dysfunction, which can strain marital relationships and further reduce quality of life. So, the aim of the study is to assess the quality of life among married women with polycystic ovary syndrome.<br> <b>Methods:</b> Cross sectional research design is used to assess the health-related quality of life (HRQoL) among 102 married Egyptian women diagnosed with PCOS attending the gynecological outpatient clinic and Assisted Reproductive Technology unit at Women&#39;s Health Hospital, Assiut University, Egypt during the period from March, to October, 2024. The data gathered by using a structure Interview questionnaire and polycystic ovary syndrome quality of life questionnaire which recorded on 3-point Likert scaling per domain.<br> <b>Results:</b> Data were analyzed using SPSS version 26 and using Chi-square test. The mean age of married women was (31.33 &plusmn; 4.70) years. The majority of women (70.6%) have irregular menstruation and (50.0%) of women had primary infertility. furthermore, the duration of marriage were 5.0 (1.0-14.0) years. One half of the women had average quality of life and the total score of quality of life were 2.20 &plusmn; 0.27.<br> <b>Conclusion:</b> PCOS have negative impact on quality of life of married women. Findings highlight the need for nurse-led educational interventions focusing on lifestyle modification.</span></span></span></div> Health-Related Quality of Life, infertility, Married women, polycystic ovary syndrome 10 10 http://jrh.gmu.ac.ir/browse.php?a_code=A-10-2846-1&slc_lang=en&sid=1 Asmaa Abo Bakr Helmy asmaabakr@aun.edu.eg 100319475328460045816 100319475328460045816 Yes Faculty of Nursing, Assiut University, Egypt Mervat Ali Khamis zeiad97@aun.edu.eg 100319475328460045817 100319475328460045817 No Faculty of Nursing, Assuit University, Egypt Heba Mostafa Mohamed hebamostafa@aun.edu.eg 100319475328460045818 100319475328460045818 No Faculty of Nursing, Assiut University, Egypt