en اثر یک جلسه فعالیت همزمان بر سطوح لپتین و شاخص مقاومت به انسولین در مردان غیر فعال ● Psychosocial Health مقاله اصيل پژوهشي Orginal Article مقاله به صورت لاتین ارسال شده است ABSTRACT Physical activity is known to influence and regulate leptin hormone secretion, which assists in the regulation of body weight and energy homeostasis. The purpose of the present study was to investigate the effects of a single session of concurrent exercise on leptin levels and insulin resistance, until 24 h post-exercise. Ten male subjects (22.9&plusmn;1.7 years) healthy volunteer performed a single session of concurrent aerobic and resistance exercise [Aerobic exercise: 60%-70% of their maximal oxygen up take for 20 min and resistance exercise: 2 sets of 10 repetitions at 70% of 1 repetition maximum]. Leptin, glucose, insulin and insulin resistance index were measured before and 24 h after exercise. Significant difference was observed between serum leptin levels (5.75&plusmn;1.06 ng.ml-1 vs, 5.06&plusmn;0.62), insulin resistance index (1.21&plusmn;0.18, vs. 1.03&plusmn;0.13) and insulin concentration (6.02&plusmn;0.54 U&Iota;&mu;.ml-1 vs, 5.30&plusmn;0.44). However, serum glucose levels (4.52&plusmn;0.27 mmol.l-1 vs., 4.37&plusmn;0.36) remained unchanged before and 24 h post-exercise. Significant correlations was observed between insulin resistance index to insulin levels (r=0.97, P=0.000) and glucose (r=0.91, P=0.000) and also between serum leptin to insulin levels (r=0.73, P=0.02) and insulin resistance index (r=0.68, P=0.038) (P<0/05). Results of this study indicated that even a single session of concurrent aerobic and resistance exercise with significant change in leptin levels could have positive effects on insulin resistance index. مقاله به صورت لاتین ارسال شده است Exercise, Insulin resistance, Leptin 314 322 http://jrh.gmu.ac.ir/browse.php?a_code=A-10-579-1&slc_lang=en&sid=1 Mohammad Ali Azarbayjani محمد علی آذربایجانی m_azarbayjani@iauctb.ac.ir 100319475328460011987 100319475328460011987 No Islamic Azad University, Central Tehran Branch, Tehran Bahram Abedi بهرام عابدی abedi_bahram2000@yahoo.com 100319475328460011988 100319475328460011988 Yes Sciences, Islamic Azad University, Mahallat Branch, Mahallat Mohamad Javad Rasaee محمد جواد رسایی rasaee_mj@yahoo.com 100319475328460011989 100319475328460011989 No Tarbiat Modares University. Tehran Firouzeh Dehghan فیروزه دهقان 100319475328460011990 100319475328460011990 No University of Malaya, Kuala lumpur, Malaysia