en ● Disease Control مقاله اصيل پژوهشي Orginal Article <div style="text-align: justify;"><strong>Background</strong>: The coronavirus disease 2019 (COVID-19) created a global public health emergency, impacting countries worldwide, including Iran. This study investigated the epidemiological characteristics, clinical features, and mortality predictors of Iranian COVID-19 patients admitted to Bohlool Hospital in Gonabad, Iran.<br> <strong>Methods</strong>: This retrospective cross-sectional study involved 1596 COVID-19 patients admitted to Bohlool Hospital in Gonabad, Iran, from February 2020 to November 2021. Data on demographic factors, clinical features, and hospitalization outcomes were gathered from patients&rsquo; medical records at the medical care monitoring center (MCMC) and analyzed using the logistic regression model.<br> <strong>Results</strong>: The median age of the patients was 61.0 years (interquartile range: 32.0). Respiratory distress (57.1%), fever (37.3%), and cough (32.5%) were the most common symptoms reported. Comorbidities, including hypertension (28.8), cardiovascular disease (CVD) (15.4%), and diabetes (15.2%), were prevalent among the patients. The overall mortality rate was 12.8%. The findings of the logistic regression model indicated that patients aged 15-44 and 45-64 had lower mortality odds compared to older age groups (odds ratio [OR]=0.14 (95% confidence interval [CI]; 0.08%, 0.27%); OR= 0.32 (95% CI; 0.21%, 0.50%), respectively%). The respiratory distress (OR=1.87, 95% CI; 1.29%, 2.70%), impaired consciousness (OR=9.27, 95% CI; 5.48%, 15.67%), cancer (OR=3.53, 95% CI; 1.40%, 8.92%), diabetes (OR=1.61, 95% CI; 1.04%, 2.49%), and chronic kidney disease (CKD) (OR=5.00, 95% CI; 1.92%, 13.02%) were significantly associated with higher mortality rates.<br> <strong>Conclusion</strong>: COVID-19 patients with older age, respiratory distress, impaired consciousness, cancer, diabetes, or CKD face significantly higher mortality rates, underscoring the need for increased attention and care for them to prevent serious outcomes.<br> &nbsp;</div> COVID-19, Coronavirus, Epidemiology, Mortality, Public health, Iran 505 516 http://jrh.gmu.ac.ir/browse.php?a_code=A-10-646-2&slc_lang=en&sid=1 Ali Alami alialami65@hotmail.com 100319475328460041171 100319475328460041171 No Department of Epidemiology & Biostatistics, Social Determinants of Health Research Center, School of Health, Gonabad University of Medical Sciences, Gonabad, Iran. Abdoljavad Khajavi fmhz.uni@gmail.com 100319475328460041172 100319475328460041172 No Department of Social Medicine, School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran. Mitra Tavakolizadeh mi.tavakoly@yahoo.com 100319475328460041173 100319475328460041173 No Clinical Reasearch Development Unit, Bohlool Hospital, Gonabad University of Medical Sciences, Gonabad, Iran. Javad Sadeghinasab jsadeghinasab@gmail.com 100319475328460041174 100319475328460041174 No Department of Pediatrics, Social Determinants of Health Research Center, School of Medicine, Bohlool Hospital, Gonabad University of Medical Sciences, Gonabad, Iran. Fatemeh Mohammadzadeh fmhz.uni@gmail.com 100319475328460041175 100319475328460041175 Yes Department of Epidemiology & Biostatistics, Social Determinants of Health Research Center, School of Health, Gonabad University of Medical Sciences, Gonabad, Iran.