en ● Disease Control گزارش کوتاه Short Communication <div style="text-align: justify;">A Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide. Many risk factors are associated with NAFLD, such as a sedentary lifestyle and obesity. This study aimed to investigate the association between disease severity, obesity, and physical activity levels in adults with NAFLD. A total of 280 adults with NAFLD were selected by a gastroenterologist using convenience sampling. NAFLD severity was assessed by ultrasound, and participants&rsquo; physical activity was evaluated using the short version of the International Physical Activity Questionnaire. Regarding NAFLD grade, 24.6% were grade 1, 63.2% were grade 2, and 12.2% were grade 3. The mean body mass index and waist circumference of the study participants were 29.19&plusmn;4.14 kg/m2 and 100.99&plusmn;9.24 cm, respectively. A significant positive relationship was observed between the degree of general obesity and NAFLD severity. As obesity increased, NAFLD severity also increased (P=0.045). A significant inverse relationship was observed between the level of physical activity and NAFLD grade (P=0.002). Considering the association between NAFLD grade, obesity, and physical activity, it is recommended that health and educational programs be developed to promote a healthy lifestyle and physical activity to reduce the prevalence of obesity and NAFLD.</div> Nonalcoholic fatty liver disease (NAFLD), General obesity, Central obesity, Physical activity, Adults  95 102 http://jrh.gmu.ac.ir/browse.php?a_code=A-10-2684-1&slc_lang=en&sid=1 Mehrdad Kianmehr www.m.kianmehr@gmail.com 100319475328460044201 100319475328460044201 No Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran Maryam Rafraf rafrafm@tbzmed.ac.ir, rafrafm2000@yahoo.com 100319475328460044202 100319475328460044202 Yes Nutrition Research Center, Department of Community Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran. Roghayeh Molani-Gol molanigol@tbzmed.ac.ir 100319475328460044203 100319475328460044203 No Department of Community Nutrition, Nutrition Research Center, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran. Mojtaba Kianmehr Kianmehr.m@gmail.com 100319475328460044204 100319475328460044204 No Department of Medical Physics, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran. Alireza Hosseini Dr.alireza.hosseini59@gmail.com 100319475328460044205 100319475328460044205 No Department of Internal Medicine, Faculty of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran.