Volume 10, Issue 5 (Sep & Oct 2020)                   J Research Health 2020, 10(5): 287-294 | Back to browse issues page

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Yosefi Chermahini Z, Taghian F, Hedayati M. Effects of Combined Training on the Levels of Obestatin, Ghrelin, and Insulin Resistance in Overweight Women. J Research Health 2020; 10 (5) :287-294
URL: http://jrh.gmu.ac.ir/article-1-1784-en.html
1- Department of Physical Education and Sport Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran.
2- Department of Physical Education and Sport Sciences, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran. , f_taghian@yahoo.com
3- Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences,Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Abstract:   (1514 Views)
Background: The present quasi-experimental and field research was conducted to evaluate the effect of combined exercises on the levels of obestatin and ghrelin in overweight women.
Methods: The study subjects consisted of 34 overweight women with a Mean±SD age of 30.29±4.66 years, a Mean±SD height of 165.11±5.56 cm, a Mean±SD weight of 74.64±7.33 kg, a Mean±SD body mass index of 27.35±1.74 kg/m2, which were selected purposefully and randomly, and assigned to the experimental (n=17) and control (n=17) groups. At first, venous blood samples were taken from subjects after 12 h overnight fasting to measure the levels of ghrelin, obestatin, glucose, insulin, and insulin resistance. Then, the participants of the experimental group participated in a combined exercise program, including warming up, aerobic training, resistance training, and cooling down. All these variables were re-measured after 12 weeks and the obtained data were analyzed. The paired t test was used for intra-group comparison and independent t test was performed for inter-group comparison.
Results: The findings of this study showed that body weight, BMI, waist circumference, glucose level, and ghrelin-obestatin ratio were significantly different between the experimental and the control groups (P≤0.05) after 8 weeks of combined exercise training, but differences in ghrelin, obestatin, insulin levels, and insulin resistance were not significant between the experimental and control groups (P≤0.05).
Conclusion: The combined exercise training, therefore, seems to be a suitable method for weight loss, body composition, waist circumference, glucose level, and ghrelin-obestatin ratio.
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Type of Study: Orginal Article | Subject: ● International Health
Received: 2019/06/10 | Accepted: 2019/07/16 | Published: 2020/09/1

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