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Pain is a natural feeling, perception, emotion, and reflection of all human beings and often comes along with mental and health problems which is experienced physically (pain, disease, injury and consequently death) and mentally (sorrow, fear and despair). This study aims to investigate the role of positive affection on predicting the aspects of pain perception in patients with MS. Forty three patients were selected by sampling from the hospitals affiliated with Zahedan University of Medical Sciences, who have filled in the questionnaire about the positive affection and pain perception. The data were analyzed using the correlation and Regression methods. The regression results showed that the positive affection is a significant predictor of pain perception (0.27).Thus, it is inferred that the positive affection has effects on pain perception of MS patients. Participating in group counseling sessions, and cultural ans sport activities that improve the positive affections may have significant role in alleviating pain MS patients

Keywords: Pain Perception, Positive Affection, MS

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